The Swiss Academy of Medical Sciences (SAMS) advocates close links between clinical practice and medical science and dialogue with society. Accordingly, it supports the implementation of open access. The SAMS takes the view that open access to research results is the best way of ensuring and improving the availability of information for researchers, healthcare professionals, patients and the general public. In view of the latest global developments in open access described in this position paper, the SAMS calls on publishers and scientific actors to facilitate and expedite the transition to open access, in order to maximize the benefits of medical research for society.